Phospholipase C gamma 1 antibody (AA 1192-1291)

Catalog No. ABIN562265

The Mouse Monoclonal anti-Phospholipase C gamma 1 antibody has been validated for WB, ELISA, IF and PLA. It is suitable to detect Phospholipase C gamma 1 in samples from Human. There is 1 publication available.

Quick Overview for Phospholipase C gamma 1 antibody (AA 1192-1291) (ABIN562265)

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Phospholipase C gamma 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Proximity Ligation Assay (PLA)

Clone: 2A2

Product Details anti-Phospholipase C gamma 1 Antibody

Binding Specificity: AA 1192-1291

Purpose: Mouse monoclonal antibody raised against a partial recombinant PLCG1.

Sequence: LKNNYSEDLE LASLLIKIDI FPAKQENGDL SPFSGTSLRE RGSDASGQLF HGRAREGSFE SRYQQPFEDF RISQEHLADH FDSRERRAPR RTRVNGDNRL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PLCG1 (NP_002651, 1192 a.a. ~ 1291 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Phospholipase C gamma 1 antibody (ABIN562265)

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).

Target Details for Phospholipase C gamma 1

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Alternative Name: PLCG1

Background: Full Gene Name: phospholipase C, gamma 1
Synonyms: PLC-II,PLC1,PLC148,PLCgamma1

Gene ID: 5335

NCBI Accession: NM_002660

Pathways: RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling